You're already seen some iTunes-optimizing tips in this very blog-o-rama, but now MakeUseOf.com has given us the equivalent of "Everything You Always Wanted To Know About iTunes, But Were Too Cheap To Pay For The Privelege Of Finding Out."
- automatically organize and tag your music
- add lyrics & cover art to your songs
- share your iTunes library with others
- create ring tones from your songs
- access your iTunes library from other PCs and mobile devices
- control iTunes via the iPhone or even using your hands and feet
- use AppleScripts
- use iTunes shortcuts
And the proverbial "so much more."